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1

Elongation factor Tu: a molecular switch in protein biosynthesis

Albert Weijland, Kim Harmark, Robbert H. Cool, Pieter H. Anborgh, Andrea Parmeggiani

Journal:

Molecular Microbiology

Year:

1992

Language:

english

File:

PDF, 2.26 MB

english, 1992

2

Substitution of histidine-84 and the GTPase mechanism of elongation factor Tu

Cool, Robbert H., Parmeggiani, Andrea

Journal:

Year:

1991

Language:

english

File:

PDF, 613 KB

english, 1991

3

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N)

van den Berghe, Nina, Cool, Robbert H, Horn, Gudrun, Wittinghofer, Alfred

Journal:

Year:

1997

Language:

english

File:

PDF, 381 KB

english, 1997

4

Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors †

Reis, Carlos R., van der Sloot, Almer M., Szegezdi, Eva, Natoni, Alessandro, Tur, Vicente, Cool, Robbert H., Samali, Afshin, Serrano, Luis, Quax, Wim J.

Journal:

Year:

2009

Language:

english

File:

PDF, 4.25 MB

english, 2009

5

The Ras Mutant D119N Is Both Dominant Negative and Activated

Cool, Robbert H., Schmidt, Gudula, Lenzen, Christian U., Prinz, Heino, Vogt, Dorothee, Wittinghofer, Alfred

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 153 KB

english, 1999

6

S-Decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1)

Robbert H. Cool, Marloes K. Veenstra, Wim van Klompenburg, René I. R. Heyne, Michael Müller, Elisabeth G. E. de Vries, Hendrik W. van Veen, Wil N. Konings

Journal:

Year:

2002

Language:

english

File:

PDF, 514 KB

english, 2002

7

Neural connectivity during reward expectation dissociates psychopathic criminals from non-criminal individuals with high impulsive/antisocial psychopathic traits

Geurts, Dirk E.M., von Borries, Katinka, Volman, Inge, Bulten, Berend Hendrik, Cools, Roshan, Verkes, Robbert-Jan

Journal:

Social Cognitive and Affective Neuroscience

Year:

2016

Language:

english

File:

PDF, 384 KB

english, 2016

8

Heterologous production of Escherichia coli penicillin G acylase in Pseudomonas aeruginosa

Joanna Krzeslak, Peter Braun, Rome Voulhoux, Robbert H. Cool, Wim J. Quax

Journal:

Journal of Biotechnology

Year:

2009

Language:

english

File:

PDF, 651 KB

english, 2009

9

NMR study of the phosphate-binding elements of Escherichia coli elongation factor Tu catalytic domain

Lowry, David F., Cool, Robbert H., Redfield, Alfred G., Parmeggiani, Andrea

Journal:

Year:

1991

Language:

english

File:

PDF, 742 KB

english, 1991

10

Human cognitive flexibility depends on dopamine D2 receptor signaling

Mieke van Holstein, Esther Aarts, Marieke E. van der Schaaf, Dirk E. M. Geurts, Robbert J. Verkes, Barbara Franke, Martine R. van Schouwenburg, Roshan Cools

Journal:

Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 467 KB

english, 2011

11

Targeting AML through DR4 with a novel variant of rhTRAIL

Eva Szegezdi, Carlos R. Reis, Almer M. van der Sloot, Alessandro Natoni, Aoife O’Reilly, Janice Reeve, Robbert H. Cool, Michael O’Dwyer, Steven Knapper, Luis Serrano, Wim J. Quax, Afshin Samali

Journal:

Journal of Cellular and Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

12

Structure-function relationships of elongation factor Tu : Isolation and activity of the guanine-nucleotide-binding domain

Michael JENSEN, Robbert H. COOL, Kim K. MORTENSEN, Brian F. C. CLARK, Andrea PARMEGGIANI

Journal:

Year:

1989

Language:

english

File:

PDF, 1.13 MB

english, 1989

13

Kinetic Analysis by Fluorescence of the Interaction between Ras and the Catalytic Domain of the Guanine Nucleotide Exchange Factor Cdc25 Mm †

Lenzen, Christian, Cool, Robbert H., Prinz, Heino, Kuhlmann, Jürgen, Wittinghofer, Alfred

Journal:

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

14

Opposite effects of cannabis and cocaine on performance monitoring

Spronk, Desirée B., Verkes, Robbert J., Cools, Roshan, Franke, Barbara, Van Wel, Janelle H.P., Ramaekers, Johannes G., De Bruijn, Ellen R.A.

Journal:

European Neuropsychopharmacology

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

15

10.1038/24884

Bos, Johannes L., de Rooij, Johan, Zwartkruis, Fried J. T., Verheijen, Mark H. G., Cool, Robbert H., Nijman, Sebastian M. B., Wittinghofer, Alfred

Journal:

Year:

1998

Language:

english

File:

PDF, 489 KB

english, 1998

16

Receptor-specific TRAIL as a means to achieve targeted elimination of activated

Arabpour, Mohammad, Cool, Robbert, Faber, Klaas Nico, Quax, Wim J, Haisma, Hidde J

Journal:

Journal of Drug Targeting

Year:

2016

Language:

english

File:

PDF, 1.55 MB

english, 2016

17

Dopaminergic drug effects during reversal learning depend on anatomical connections between the orbitofrontal cortex and the amygdala

van der Schaaf, Marieke E., Zwiers, Marcel P., van Schouwenburg, Martine R., Geurts, Dirk E. M., Schellekens, Arnt F. A., Buitelaar, Jan K., Verkes, Robbert Jan, Cools, Roshan

Journal:

Frontiers in Neuroscience

Year:

2013

Language:

english

File:

PDF, 2.27 MB

english, 2013

18

Characterization of Saccharomyces cerevisiae Ras1p and Chimaeric Constructs of Ras Proteins Reveals the Hypervariable Region and Farnesylation as Critical Elements in the Adenylyl Cyclase Signaling Pathway

Créchet, Jean-Bernard, Cool, Robbert H., Jacquet, Eric, Lallemand, Jean-Yves

Journal:

Year:

2003

Language:

english

File:

PDF, 126 KB

english, 2003

19

Small-molecule inhibitors of macrophage migration inhibitory factor (MIF) as an emerging class of therapeutics for immune disorders

Kok, Tjie, Wasiel, Anna A., Cool, Robbert H., Melgert, Barbro N., Poelarends, Gerrit J., Dekker, Frank J.

Journal:

Drug Discovery Today

Year:

2018

Language:

english

File:

PDF, 506 KB

english, 2018

20

COMT Val158Met modulates the effect of childhood adverse experiences on the risk of alcohol dependence

Arnt F. A. Schellekens, Barbara Franke, Bart Ellenbroek, Alexander Cools, Cor A. J. de Jong, Jan K. Buitelaar, Robbert-Jan Verkes

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

21

Analysis of a substrate specificity switch residue of cephalosporin acylase

Charles F Sio, Linda G Otten, Robbert H Cool, Wim J Quax

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

22

DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer

Yu, Rui, Albarenque, Stella Maris, Cool, Robbert H, Quax, Wim J, Mohr, Andrea, Zwacka, Ralf M

Journal:

Cancer Biology & Therapy

Year:

2014

Language:

english

File:

PDF, 4.95 MB

english, 2014

23

1000. Down-Regulating the Epithelial Glycoprotein-2 Promoter Utilizing Engineered Zinc Finger Protein Transcription Factors

Gommans, Willemijn M., McLaughlin, Pamela M.J., Cool, Robbert, Lindhout, Beatrice I., van der Zaal, Bert, Haisma, Hidde J., Rots, Marianne G.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

24

Lipase A gene transcription in Pseudomonas alcaligenes is under control of RNA polymerase σ54 and response regulator LipR

Joanna Krzeslak, Evelina Papaioannou, Ronald van Merkerk, Krisztina A. Paal, Rainer Bischoff, Robbert H. Cool, Wim J. Quax

Journal:

FEMS Microbiology Letters

Year:

2012

Language:

english

File:

PDF, 323 KB

english, 2012

25

Deinococcus radiodurans can interfere with quorum sensing by producing an AHL-acylase and an AHL-lactonase

Koch, Gudrun, Nadal-Jimenez, Pol, Cool, Robbert H., Quax, Wim J.

Journal:

FEMS Microbiology Letters

Year:

2014

Language:

english

File:

PDF, 882 KB

english, 2014

26

Mutagenesis of the NH2-terminal domain of elongation factor Tu

Füsun Gümü§el, Robbert H. Cool, Albert Weijland, Pieter H. Anborgh, Andrea Parmeggiani

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1990

Language:

english

File:

PDF, 615 KB

english, 1990

27

Minimum requirements for specific binding of RNA and coat protein of alfalfa mosaic virus

Douwe Zuidema, Robbert H. Cool, E.M.J. Jaspars

Journal:

Year:

1984

Language:

english

File:

PDF, 2.14 MB

english, 1984

28

483. Amygdala Response Predicts Clinical Symptom Reduction in Patients with Borderline Personality Disorder

Geurts, Dirk, van den Heuvel, Thom, Huys, Quentin, Verkes, Robbert-Jan, Cools, Roshan

Journal:

Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 57 KB

english, 2017

29

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins

Vittorio Carrera, Andrea Moroni, Enzo Martegani, Celina Volponi, Robbert H. Cool, Lilia Alberghina, Marco Vanoni

Journal:

Year:

1998

Language:

english

File:

PDF, 194 KB

english, 1998

30

7-Hydroxycoumarins are Affinity-based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor

Xiao, Zhangping, Chen, Deng, Song, Shanshan, van der Vlag, Ramon, van der Wouden, Petra E., van Merkerk, Ronald, Cool, Robbert, Hirsch, Anna K.H, Melgert, Barbro, Quax, Wim J., Poelarends, Gerrit J.,

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.01 MB

2020

31

Methylphenidate boosts choices of mental labor over leisure depending on striatal dopamine synthesis capacity

Hofmans, Lieke, Papadopetraki, Danae, van den Bosch, Ruben, MÃ¤Ã¤ttÃ¤, Jessica I., FrobÃ¶se, Monja I., Zandbelt, Bram. B., Westbrook, Andrew, Verkes, Robbert-Jan, Cools, Roshan

Journal:

Neuropsychopharmacology

Year:

2020

File:

PDF, 1.47 MB

2020

32

A Novel Genetic Selection System for Improved Enantioselectivity of Bacillus subtilis Lipase A

Ykelien L. Boersma, Melloney J. Dröge, Almer M. van der Sloot, Tjaard Pijning, Robbert H. Cool, Bauke W. Dijkstra, Wim J. Quax

Journal:

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

33

Dynamic interaction of cAMP with the rap guanine-nucleotide exchange factor epac1

Astrid Kraemer, Holger R. Rehmann, Robbert H. Cool, Christiane Theiss, Johan de Rooij, Johannes L. Bos, Alfred Wittinghofer

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 239 KB

english, 2001

34

Structure Determination of the Ras-Binding Domain of the Ral-Specific Guanine Nucleotide Exchange Factor Rlf †,‡

Esser, Dirk, Bauer, Bettina, Wolthuis, Rob M. F., Wittinghofer, Alfred, Cool, Robbert H., Bayer, Peter

Journal:

Year:

1998

Language:

english

File:

PDF, 167 KB

english, 1998

35

Acute effects of cocaine and cannabis on reversal learning as a function ofCOMTandDRD2genotype

Spronk, Desirée B., Van der Schaaf, Marieke E., Cools, Roshan, De Bruijn, Ellen R. A., Franke, Barbara, van Wel, Janelle H. P., Ramaekers, Johannes G., Verkes, Robbert J.

Journal:

Psychopharmacology

Year:

2016

Language:

english

File:

PDF, 618 KB

english, 2016

36

Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis

Wang, Yizhou, van Assen, Aart H.G., Reis, Carlos R., Setroikromo, Rita, van Merkerk, Ronald, Boersma, Ykelien L., Cool, Robbert H., Quax, Wim J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.22 MB

english, 2017

37

The cognitive effects of a promised bonus do not depend on dopamine synthesis capacity

Hofmans, Lieke, van den Bosch, Ruben, MÃ¤Ã¤ttÃ¤, Jessica I., Verkes, Robbert-Jan, Aarts, Esther, Cools, Roshan

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.50 MB

2020

38

Mutational Analysis of a Key Residue in the Substrate Specificity of a Cephalosporin Acylase

Linda G. Otten, Charles F. Sio, Almer M. van der Sloot, Robbert H. Cool, Wim J. Quax

Journal:

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

39

Characterization of the interaction between human complement protein C4 and a single-chain variable fragment antibody by capillary electrophoresis and surface plasmon resonance

Reza M. Seifar, Robbert H. Cool, Wim J. Quax, Rainer Bischoff

Journal:

ELECTROPHORESIS

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

40

A highly active adipyl-cephalosporin acylase obtained via rational randomization

Linda G. Otten, Charles F. Sio, Carlos R. Reis, Gudrun Koch, Robbert H. Cool, Wim J. Quax

Journal:

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

41

Effects of ions on the intrinsic activities of c-H-ras protein p21 : A comparison with elongation factor Tu

Michel-Yves MISTOU, Robbert H. COOL, Andrea PARMEGGIANI

Journal:

Year:

1992

Language:

english

File:

PDF, 740 KB

english, 1992

42

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1

Görlach, Agnes, Berchner-Pfannschmidt, Utta, Wotzlaw, Christoph, Cool, Robbert, Fandrey, Joachim, Acker, Helmut, Jungermann, Kurt, Kietzmann, Thomas

Journal:

Thrombosis and Haemostasis

Year:

2003

Language:

english

File:

PDF, 313 KB

english, 2003

43

The functional and structural roles of residues Gln114 and Glu117 in elongation factor Tu

Kim HARMARK, Robbert H. COOL, Brian F. C. CLARK, Andrea PARMEGGIANI

Journal:

Year:

1990

Language:

english

File:

PDF, 656 KB

english, 1990

44

Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs

Sinitski, Dzmitry, Gruner, Katrin, Brandhofer, Markus, Kontos, Christos, Winkler, Pascal, Reinstädler, Anja, Bourilhon, Priscila, Xiao, Zhangping, Cool, Robbert H., Kapurniotu, Aphrodite, Dekker, Fran

Journal:

Journal of Biological Chemistry

Year:

2019

File:

PDF, 2.71 MB

2019

45

Early-Onset Alcohol Dependence Increases the Acoustic Startle Reflex

Arnt F. A. Schellekens, Peter C. R. Mulders, Bart Ellenbroek, Cor A. J. de Jong, Jan K. Buitelaar, Alexander Cools, Robbert-Jan Verkes

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2012

Language:

english

File:

PDF, 218 KB

english, 2012

46

The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls

Arnt F.A. Schellekens, Armand W.A.A. van Oosterwijck, Bart Ellenbroek, Cor A.J. de Jong, Jan K. Buitelaar, Lex Cools, Robbert-Jan Verkes

Journal:

European Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

47

Functional Role of the Noncatalytic Domains of Elongation Factor Tu in the Interactions with Ligands †

Cetin, Rengül, Anborgh, Pieter H., Cool, Robbert H., Parmeggiani, Andrea

Journal:

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

48

An ABC-type multidrug transporter of Lactococcus lactis possesses an exceptionally broad substrate specificity

Gerrit J. Poelarends, Piotr Mazurkiewicz, Monique Putman, Robbert H. Cool, Hendrik W.van Veen, Wil N. Konings

Journal:

Drug Resistance Updates

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000

49

Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells

COOL, Robbert H., MERTEN, Evelyne, THEISS, Christiane, ACKER, Helmut

Journal:

Biochemical Journal

Year:

1998

Language:

english

File:

PDF, 302 KB

english, 1998

50

The acylase PvdQ has a conserved function among fluorescent Pseudomonas spp.

Gudrun Koch, Pol Nadal Jimenez, Remco Muntendam, Yixi Chen, Evelina Papaioannou, Stephan Heeb, Miguel Cámara, Paul Williams, Robbert H. Cool, Wim J. Quax

Journal:

Environmental Microbiology Reports

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

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